- Steroids Promotion Product (6)
- Commodities In Short Supply (8)
- New Fresh Products (8)
- Populor On Sale Products (17)
- Hot Sale Products (13)
- New Products-Steroid Orals (18)
- New Products-Steroid Injectables (12)
- New Products-peptides (10)
- New Pproducts-Raw Powders (9)
- Testosterone Steroids Raw Powders (17)
- Trenbolone Steroids Raw Powders (7)
- Nandrolone Steroids Raw Powders (4)
- Methenolone Steroids Raw Powders (2)
- Other Steroids Raw Powders (12)
- Peptide Human Growth Hormone (13)
- Other Peptide Somatotropin Drugs (13)
- Finished Oral Anabolic Steroids Tabs (18)
- Finished Injectable Anabolic Steroids (26)
- Anabolic Steroid Cinnamic (3)
No. of Employees : 50~100 86-010-85668888-218
Kigtropin HGH Human Growth Hormone,Somatropin
|Minimum Order Quantity:||1 kit|
|Delivery Time:||within a week|
|Payment Terms:||Wester Union,Moneygarms|
|Supply Ability:||100000 iu/month|
Recombinant Human Growth Hormone for Injection
【NAME OF THE MEDICINAL PRODUCT】
Generic Name: Recombinant Human Growth Hormone
Trade Name: KIGTROPIN
Recombinant Human Growth Hormone and excipients.
Molecular Formula:C990H1528N262O300S7 with 191 amino acids residues.
Origin of the Active Ingredient: KIGTROPIN is a Recombinants Human Growth Hormone.
KIGTROPIN is produced by recombinant DNA technology in E.coli secretion expression system.
KIGTROPIN has the same amino acid sequence with 191 residues as the native human growth hormone produced in the human body.
White Lyophilized powder.
Growth failure of children due to endogenous growth hormone deficiency (GHD).
In adults with growth hormone deficiency,KIGTROPIN reduces fat mass,increases muscle mass and improves energy,vitality and subjective well-being. In patients suffering from severe burns,AIDS ass°Ciated muscle wasting,or undergoing major operations,KIGTROPIN promotes wound healing,attenuates the protein-catabolic response and improves whole-body nitrogen condition after operation.
【DOSAGE AND ADMINISTRATION】
Before administration, add 1ml of sterile water for injection to the rhGH vial of Lyophilized powder along the wall slowly. Shake it gently to fully dissolve the powder to get clarified solution. DO NOT shake violently.For anti-aging, general health & healing, fat mobilization, a dose of 2-3 IU's per day will be sufficient for the majority. A dose of 1.5 to 2.0 IU's is considered to be a full replacement dose for those in their middle-age and beyond.For gaining lean muscle and substantially improving body composition, a dose of 4-8 IUs per day will be necessary. Most people will respond very well at a dose of 4-5 IU's per day. For maximum benefit in this regard, the addition of Testosterone, Insulin, and low-dose t3 would be something to seriously consider. More on this in our comparative cycle guide of HGH/Insulin/IGF.
The recommended dosage for injection is 0.1-0.15IU/kg/day, inject before sleeping daily at the same time and the injectionsite should be changes frequently to prevent lipoatrophy at the site, or follow the physician’s advice.
Growth hormone may induce transient hyperglycosemia, which usually recover to normal level over time or after drug discontinuation.
About 1% children with microsomia in the clinical trial presented side effects, which usually presented transient reactions at the injection site (pain, tingling numbness, red swelling, etc) and the symptoms of fluid retention (peripheral edema, arthralgia or myalgia).These side effects usually appear at early stage and the incidence rate decreases over time which rarely affects daily activities.
Long-term injection of recombinant human growth hormone results in antibody production in minority people, however, the affinity of the antibody is low without exact clinical significance. The antibody may be induced if the anticipant effect of growth is not achieved, which may affect the efficacy if the affinity is over 2 mg/L.
Children with closure of epiphysis are forbidden.
Patients with the progressive symptoms of tumor are forbidden.
Critical ill patients in acute sh°Ck stage of serious systematic infection are forbidden.
【WARNINGS AND PRECAUTIONS】
rhGH therapy should be conducted on exactly diagnosed GHD patients under advice of experienced d°Ctor.
For diabetes patients, dosage of anti-glucourea drugs should be adjusted during rhGH therapy.
For patients whose GHD were caused by encephaloma or encephalic wound, the progress and relapse possibility of potential diseases should be closely monitored.
For ACTH deficiency patients, dosage of ATCH should be adjusted because the growth improvement effect of rhGH could be inhibited by simultaneous using of ACTH.
Thyroid gland function should be tested regularly because clinical hypothyroidism may °Ccur to some patients during rhGH therapy. For those hypothyroid, thyroid supplementation is necessary for ensuring the therapeutic effects of rhGH.
Careful consideration should be taken if claudicating °Ccurred during rhGH therapy because the patients who suffered from end°Crine system disease (including GHD) have such a tendency that their epiphysis plates of femur are relatively easy to separate.
Growth hormone may lead to over insulin state. Attention should be paid to if lower glucose intolerance appeared.
Do not take over-dose of rhGH, one time over-dose rhGH administration can lead to high blood sugar. Long-term over-does rhGH administration can lead to acromegaly.
Injection site should often variation in case lipoatrophy.
Athletes should administer the drug with caution.
【USAGE IN PREGNANCY AND LACTATION】
It is not suitable to use.
Concurrent administration of gluc°Corticoid may inhibit the response of the hormone, therefore, the dosage of gluc°Corticoid is usually not over the equivalent dosage of 10～15 mg hydr°Cortisone/square meter body surface area.
Concurrent administration of non-androgen steroid may further promote the growth rate.
【PHARMACOLOGY AND TOXICOLOGY】
rhGH exerts the same actions of endogenous human growth hormone. It can stimulate proliferation and differentiation of epiphysis chondr°Cyte, stimulate growth of cartilage matrix cells, stimulate proliferation and differentiation of osteoblast; thus accelerate the liner growth rate and improve epiphysis width.
rhGH can promote protein synthesis in whole body; reverse the negative nitrogen equilibrium caused by wound and surgery;correct the hypoproteinemia due to severe infection or hepat°Cirrhosis; stimulate synthesis of immune globin and proliferation of lymph adenoid, macrophage and lymph°Cyte, thus enhance the ability of infection resistance; stimulate proliferation of collagen°Cyte, fibroblast and macrophage in sites of burn and surgery, thus accelerate wound healing; promote synthesis of cardi°Cytes, thus improve cardiac contractility and reduce cardiac oxygen consumption; regulate lipometabolism, thus depress serum cholesterol and low density lipoprotein's level; complement insufficiency or deficiency of growth hormone, regulate adult's lipometabolism, osteometabolism, heart and kidney function.
It is reported that the equal pharmacological effect could be achieved via subcutaneous (sc) or intramuscular (IM) administration. Even though sc may lead a higher concentration of GH in plasma, IM could also yield the same IGF-l level. The absorption of GH is the relatively slow, max often °Ccurs at 3-5 hours after injection.
Clearance of GH is via liver and kidney, the half-life of clearance is about 2-3 hours. Uncatabolized GH excreted in urea is almost immeasurable. All of the GH in circulation system exists as a complex form with GH binding proteins that make the half-life of GH prolonged.
Keep at 2~8°C in the refrigerator,away from light.
--If refrigerated between 2-8°C, it's good until expiration date.
--At room temperature (under 37°C) it's good for over 30 days.
--Use Bacteriostatic Water to reconstitute and keep in 2~8°C, it will be good for 20 days.
--Use Sterile Water to reconstitute and keep in 2~8°C. it will be good for 72 hours.
Tube-shaped antibiotics glass bottle, 10 bottles/inner box.
Pharmacopoeia of People’s Republic of China 2005 Edition 2