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IGF-1 DES somatomedins,insulin-like growth factors

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IGF-1 DES somatomedins,insulin-like growth factors

Payment & Shipping Terms:
Minimum Order Quantity: 1 kit
Packaging Details: standard
Delivery Time: within a week
Payment Terms: Wester Union,Moneygarms
Supply Ability: 100000mg/month
Description
Catalog Number L886686
Certified Level HPLC Certified
Mass Spectrum Certified
Unit size 1 mg/vial
Unit Quantity 1 Vial
Total Weight 1 mg
CAS NO. N/A
Synonyms IGF-1 DES
Molecular Formula N/A
Molecular Weight 7371.4
Sequence H-Thr-Leu-Cys-Gly-Ala-Glu-Leu-Val-Asp-Ala-Leu-Gln-Phe-Val-Cys-Gly-Asp-Arg-Gly-Phe-Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr-Gly-Ile-Val-Asp-Glu-Cys-Cys-Phe-Arg-Ser-Cys-Asp-Leu-Arg-Arg-Leu-Glu-Met-Tyr-Cys-Ala-Pro-Leu-Lys-Pro-Ala-Lys-Ser-Ala-OH
Appearance White Powder
Purity >95%(HPLC)
Identity (ESI-MS) 7371.4±7.8
Source Chemical Synthesis
Bacterial Endotoxins < 5EU/mg
Test Parameter Standard
Solubility Soluble in water or 1% acetic acid
Storage Lyophilized IGF-1 DES although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FST should be stored at 4°C between 2-7 days and for future use below -18°C.
Reports:
M120705-L886686 95.13% MS HPLC
M120710-L886686 95.04% MS HPLC
M121001-L886686 95.97% MS HPLC
The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF-1 DES is a truncated form of IGF-1, which mediates many of the growth-promoting effects of growth hormone, with the tri-peptide structure Glycine-Proline-Glutamine cleaved from the N-terminus. It has been isolated from and detected in numerous in vivo sources, including the human brain, bovine colostrum, and porcine uterus. In vitro studies demonstrate that at equal doses DES (1-3) IGF is ten times more potent than IGF-1 at stimulating hypertrophy and proliferation in cultured cells. It is likely generated through post-translational modification in the sequence of circulating mature IGF-1 via protease action.

 

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