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Thymosin β4

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Thymosin β4

Payment & Shipping Terms:
Minimum Order Quantity: 1 kit
Packaging Details: standard
Delivery Time: within a week
Payment Terms: Wester Union,Moneygarms
Supply Ability: 100000mg/month
Description
Catalog Number L668934
Certified Level HPLC Certified, Video Enhanced
Mass Spectrum Certified, Video Enhanced
Unit size 2 mg/vial
Unit Quantity 1 Vial
Total Weight 2 mg
CAS NO. 77591-33-4
Synonyms Thymosin Beta 4
Molecular Formula C212H350N56O78S
Molecular Weight 4963.44
Sequence Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr- Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH
Appearance White Powder
Purity >98%(HPLC)
Identity (ESI-MS) 4963.44±5.1
Source Chemical Synthesis
Bacterial Endotoxins < 5EU/mg
Test Parameter Standard
Solubility Soluble in water or 1% acetic acid
Storage Lyophilized Thymosin Beta 4(TB500) although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FST should be stored at 4°C between 2-7 days and for future use below -18°C.
Reports:
M120630-L668934 98.58% MS HPLC
M120705-L668934 99.67% MS HPLC
M120710-L668934 98.49% MS HPLC
M120813-L668934 98.22% MS HPLC
Ms test video http://www.youtube.com/watch?v=F_-7BVkJ__g
Hplc test video http://www.youtube.com/watch?v=ztBkg3UyqhE
Thymosin Beta 4 (Tβ4) is a major intracellular G-actin-sequestering peptide with amino acid sequence Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES. Studies have shown that Tβ4 levels decreased significantly in corneas of diabetic patients compared with healthy subjects, and exogenous Tβ4 administration would promote wound healing in diabetic and nondiabetic corneas. Tβ4 could also improve glucose intolerance and ameliorated insulin resistance in KK mouse, which indicated that Tβ4 may be a potential alternative insulin sensitizer for the treatment of type 2 diabetes mellitus.

 

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